If you enable this setting, DirectInvoke will be enabled which will allow Sharepoint files to be opened directly from the editing application.
If you disable this setting, DirectInvoke will not be enabled and Sharepoint files will sometimes be downloaded instead of invoked directly.
| Registry Hive | HKEY_LOCAL_MACHINE or HKEY_CURRENT_USER |
| Registry Path | Software\Policies\IE Tab\IE Tab |
| Value Name | EnableDirectInvoke |
| Value Type | REG_DWORD |
| Enabled Value | 1 |
| Disabled Value | 0 |